Martin-Luther-Universität Halle-Wittenberg

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Prof. Dr. Peter Imming

Wolfgang-Langenbeck-Str. 4
06120 Halle (Saale)

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PROJECT OBJECTIVES

The aim of the TRI‐SUSTAIN project is to develop a novel  three‐pronged  integrated approach towards the goals of bioeconomic  value‐chains,  ecological and therapeutic sustainability, accompanied by a  Graduate  School.


LATEST NEWS

December 2019: Mthandazo Dube goes on a field trip to collect anthelmintic plants

Birhanu Nigusse Kahsay working on an ATR-FTIR spectrometer at the MLU

Birhanu Nigusse Kahsay working on an ATR-FTIR spectrometer at the MLU

Birhanu Nigusse Kahsay working on an ATR-FTIR spectrometer at the MLU

In December 2019 Mthandazo Dube, a PhD student at the MLU went to Botswana to collect plants that are used in traditional medicine against parasitic worms. He collected a total of 25 samples that he will test  against the free living nematode Caenorhabditis elegans with the hope of isolating anthelmintic compounds.


PROJECT PARTNERS


PUBLICATIONS

Ghislain Wabo Fotso, Linda Mogue Kamdem, Mthandazo Dube, Serge Alain Fobofou, Albert Ndjie Ebene, Bonaventure Tchaleu Ngadjui: Antimicrobial secondary metabolites from the stem barks and leaves of Monotes kerstingii Gilg (Dipterocarpaceae). Fitoterapia 137 (2019) 104239.

Ruth Feilcke, Georgette Arnouk, Boingotlo Raphane, Khumoekae Richard, Ian Tietjen, Kerstin Andrae-Marobela, Frank Erdmann, Susanne Schipper, Katja Becker, Norbert Arnold, Andrej Frolov, Norbert Reiling, Peter Imming, Serge A.T. Fobofou: Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphophia foliosa Hochst. Journal of Pharmaceutical and Biomedical Analysis 174 (2019) 277-285.

Serge A.T. Fobofou, Kaleab Asres, Norbert Arnold, Peter Imming: New source report: Chemical constituents of Hypericum quartinianum (Hypericeae), a sub-Saharan African plant species. Biochemical Systematic and Ecology 85 (2019) 46-49.

Efrem N. Tessema,  Reinhard Neubert, Serge A. T. Fobofou, Tsige Gebre-Mariam, Jürgen Schmidt, Katrin Franke, Norbert Arnold: Anthelmintic activity-guided  fractionation and GC-MS analysis of extracts from Embelia schimperi fruits. International Journal of Applied Research in Natural Products 11 (2018) 11-16.


THESES COMPLETED

Anika Lins: "The antimycobacterial effect of benzothiazinones and their analogues against Mycobacterium aurum and structure-activity
relationships of the compounds" Diploma Thesis (Pharmacy) Halle 2019.
Examiners: Prof. Dr. Peter Imming, MLU Halle, Prof. Dr. Kerstin
Andrä-Marobela, University of Botswana.

Simone Wappler: "Knipholonanthrone derivatives: Synthetic access and pharmacological activity." Diploma Thesis (Pharmacy) Halle 2019.
Examiners: Prof. Dr. Peter Imming, PD Dr. Matthias Schmidt, MLU Halle, Prof. Dr. Kerstin Andrä-Marobela, University of Botswana.


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