Martin-Luther-Universität Halle-Wittenberg


Prof. Dr. Peter Imming

Kurt Mothes Str. 3
06120 Halle (Saale)


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The aim of the TRI‐SUSTAIN project is to develop a novel three‐pronged integrated approach towards the goals of bioeconomic value‐chains, ecological and therapeutic sustainability, accompanied by a Graduate School.


November 2022: New Publication in Plants

Mthandazo Dube and Boingotlo Raphane, both PhD students from TRISUSTAIN published an article in Plants journal.

Schistosomiasis and soil-transmitted helminths are some of the priority neglected tropical diseases targeted for elimination by the World Health Organization. Although Botswana has a modern healthcare system, many people rely on traditional medicine to treat worm infections and schistosomiasis. In this study, ten plant species used by traditional health practitioners against worm infections were collected and tested against a set of species in vitro. Extracts of two plants, Laphangium luteoalbum and Commiphora pyaracanthoides, displayed promising anthelmintic activity against newly transformed schistosomas and adult Schistosoma mansoni. L. luteoalbum displayed 85.4% activity at 1 μg/mL against Newly Transformed Schistosoma, while Commiphora pyracanthoides displayed 78.5% activity against adult S. mansoni at 10 μg/mL. The anthelmintic activity shown by the plant samples demonstrates the importance of traditional medicine, as traditional health practitioners have knowledge about which plants to use against various ailments. Further investigations need to be carried out in order to identify the active principles in the plant extracts and validate the safety of the plant extracts through toxicological studies.   

November 2022: Successful PhD Defense

Alphonce Marealle from TRISUSTAIN has successfully defended his doctoral thesis. In his work, he describes the Search for Potential Anti-HIV-1 and Antimycobacterial Compounds from Selected Tanzanian Medicinal Plants. The study was supervised by Profs. Mainen Moshi, Ester Innocent (both MUHAS) and Kerstin-Andrae-Marobela (UoB). A kind compliment goes to Dr. Alphonce Marealle for his achievements. We appreciate his contribution to the project and wish him the very best for his future career.





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