Martin-Luther-Universität Halle-Wittenberg

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Already published publications

Innocent, Ester; Marealle, Alphonce Ignace; Imming, Peter; Moeller, Lucie: An Annotated Inventory of Tanzanian Medicinal Plants Traditionally Used for the Treatment of Respiratory Bacterial Infections.. Plants 11 (7) (2022) 931.
https://doi.org/10.3390/plants11070931   

Sirak, Betelhem, Kaleab Asres, Asrat Hailu, Mthandazo Dube, Norbert Arnold, Cecile Häberli, Jennifer Keiser, and Peter Imming: In  Vitro Antileishmanial and Antischistosomal Activities of Anemonin Isolated from the Fresh Leaves of Ranunculus multifidus Forsk. Molecules 26 (2021) 7473.
https://doi.org/10.3390/molecules26247473   

Sirak, Betelhem, Lea Mann, Adrian Richter, Kaleab Asres, Peter Imming: In Vivo Antimalarial Activity of Leaf Extracts and a Major Compound Isolated from Ranunculus multifidus Forsk. Molecules 26 (2021) 6179.
https://doi.org/10.3390/molecules26206179   

Dube, Mthandazo, Mohamad Saoud, Robert Rennert, Ghislain W. Fotso, Kerstin Andrae-Marobela, Peter Imming, Cécile Häberli, Jennifer Keiser, and Norbert Arnold: Anthelmintic Activity and Cytotoxic Effects of Compounds Isolated from the Fruits of Ozoroa insignis Del. (Anacardiaceae). Biomolecules 11 (2021).
https://doi.org/10.3390/biom11121893   

Birhanu Nigusse Kahsay, Jörg Ziegler, Peter Imming, Tsige Gebre-Mariam, Reinhard H. H. Neubert, Lucie Moeller: Free amino acid contents of selected Ethiopian plant and fungi species: a search for alternative natural free amino acid sources for cosmeceutical applications. Amino Acids (2021).
https://doi.org/10.1007/s00726-021-03008-5   

Alphonce Ignace Marealle, Mainen Moshi, Ester Innocent, Michael Qwarse, Kerstin Andrae-Marobela: Ethnomedical survey of plants used for the management of HIV and AIDS-related conditions in Mbulu District, Tanzania. Journal of Medicinal Plants Research 15 (2021) 1-21.
https://academicjournals.org/journal/JMPR/article-abstract/C3B7BAD65784   

Tesfaye Gabriel, Antheneh Belete, Frank Syrowatka, Reinhard H.H. Neubert, Tsige Gebre-Mariam:  Extraction and Characterization of Celluloses from Various Plant  Byproducts. International Journal of Biological Macromolecules 158  (2020) 1248-1258.
https://doi.org/10.1016/j.ijbiomac.2020.04.264   

Alphonce Ignace Marealle, Ester Innocent, Kerstin Andrae- Marobela, Michael Qwarse, Mainen Moshi: Ethnopharmacological Survey of Medicinal Plants Used in the Management of HIV and AIDS-Related Conditions in Makete District, Southern Highlands of Tanzania. European Journal of Medicinal Plants 31 (2020) 56-83.
https://doi.org/10.9734/ejmp/2020/v31i1430317   

Admassu Assen Adem, Anteneh Belete, Alena Soboleva, Andrej Frolov, Efrem N. Tessema, Tsige Gebre-Mariam, Reinhard H.H. Neubert: Structural characterization of plant glucosylceramides and the corresponding ceramides by UHPLC-LTQ-Orbitrap mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 192 (2020).
https://doi.org/10.1016/j.jpba.2020.113677   

Boris D. Bekono, Fidele Ntie-Kang, Pascal Amoa Onguéné, Lydia L. Lifongo, Wolfgang Sippl, Karin Fester, Luc C. O. Owono: The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019. Malaria Journal 183 (2020).
https://doi.org/10.1186/s12936-020-03231-7   

Richard Khumoekae, Cole Schonhofer, Leila B. Giron, Jocelyn Rivera-Ortiz, Silven Read, Toshitha Kannan, Natalie N. Kinloch, Aniqa Shahid, Ruth Feilcke, Simone Wappler, Peter Imming, Marianne Harris, Zabrina L. Brumme, Mark A. Brockmann, Karam Mounder, Andrew V. Kossenkov, Mohamed Abdel-Mohsen, Kerstin Andrae-Marobela, Luis J. Montaner, Ian Tietjen: The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal. Journal of Biological Chemistry 295 (2020) 14084-14099.
https://doi.org/10.1074/jbc.RA120.013031   

Ghislain Wabo Fotso, Linda Mogue Kamdem, Mthandazo Dube, Serge Alain Fobofou, Albert Ndjie Ebene, Bonaventure Tchaleu Ngadjui: Antimicrobial secondary metabolites from the stem barks and leaves of Monotes kerstingii Gilg (Dipterocarpaceae). Fitoterapia 137 (2019) 104239.

Ruth Feilcke, Georgette Arnouk, Boingotlo Raphane, Khumoekae Richard, Ian Tietjen, Kerstin Andrae-Marobela, Frank Erdmann, Susanne Schipper, Katja Becker, Norbert Arnold, Andrej Frolov, Norbert Reiling, Peter Imming, Serge A.T. Fobofou: Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphophia foliosa Hochst. Journal of Pharmaceutical and Biomedical Analysis 174 (2019) 277-285.

Serge A.T. Fobofou, Kaleab Asres, Norbert Arnold, Peter Imming: New source report: Chemical constituents of Hypericum quartinianum (Hypericeae), a sub-Saharan African plant species. Biochemical Systematic and Ecology 85 (2019) 46-49.

Efrem N. Tessema, Reinhard Neubert, Serge A. T. Fobofou, Tsige Gebre-Mariam, Jürgen Schmidt, Katrin Franke, Norbert Arnold: Anthelmintic activity-guided fractionation and GC-MS analysis of extracts from Embelia schimperi fruits. International Journal of Applied Research in Natural Products 11 (2018) 11-16.


PhD Students and Thesis Titles

Abrham Temesgen Mengstu: Development of Inhalational Starch-Based Nanoparticles of Amikacin for Improved Therapy of Tuberculosis

Admassu Assen Adem: Use of Nanoemulgel for the Delivery of Phytoceramides and Essential Oils with Mosquito Repellent Activity

Alphonce Marealle: Search for Potential Anti-HIV-1 Compounds from Selected Tanzanian Medicinal Plants

Birhanu Nigusse Kahsay: Extraction, Standardization, and Formulation of Plant Amino Acids for Dermal Applications

Boingotlo Raphane: Identification and characterization of traditional medicinal plants as sources of anti‐HIV and HIV anti‐latency therapeutic natural products

Mamo Feyissa Senbeta: Ethno-Pharmaceutical Studies of Medicinal Plants: Emphasis on Herbal Medicines Used for Treatment of HIV and Tuberculosis

Mthandazo Dube: Bioassay guided isolation and structure elucidation of anthelminthic constituents from Sub‐Saharan traditional medicinal plants

Raphael Shedafa: Development of HPTLC and HPLC-MS Fingerprinting and Other Quality Evaluation Methods from Selected Herbal Medicines in Tanzania

Tesfaye Gabriel Dalalo: Fabrication of Teff and Enset Cellulose and Starch-Based Nanogels for Controlled Delivery of Antiretrovirals


Submitted and in preparation

Ester Innocent, Alphonce I. Marealle, Peter Imming, Lucie Moeller: Natural products with potential anti-bacterial and anti-mycobacterial properties against respiratory diseases: Review of Tanzanian anti-infective plants. Journal of Herbal Medicine.

Alphonce Ignace Marealle, Ester Innocent, Kerstin Andrae-Marobela, Michael Qwarse, Mainen Moshi: Ethnopharmacological Survey of Medicinal Plants Used in the Management of HIV and AIDS-Related Conditions in Makete District, Southern Higlands of Tanzania. BMC Complementary Medicine and Therapies.

Mthandazo Dube, Ghislain Wabo Fotso, Kerstin Andrae-Marobela, Peter Imming, Norbert Arnold: Anthelmintic activity of Ozoroa insignis (Anacardiaceae) fruit extract and ginkgolic acid. Journal of Ethnopharmacology.

Birhanu Nigusse Kahsay, Lucie Moeller, Jörg Ziegler, Tsige Gebre-Mariam, Reinhard Neubert: Free Amino Acid contents of Selected Ethiopian Plant and Fungi Species: A Search for Alternative Natural Free Amino Acid Sources for Cosmeceutical Applications. Journal of Amino Acids.

Alphonce Ignace Marealle, Ester Innocent, Michael Qwarse, Mainen Moshi, Kerstin Andrae-Marobela: Medicinal Plants Used for Management of HIV and AIDS-Related Conditions in Mbulu District, Tanzania. BMC Complementary Medicine and Therapies.

Admassu Assen Adem, Anteneh Belete, Andrej Frolov, Erfrem N. Tessema, Tsige Gebre-Mariam, Reinhard H.H. Neubert: Plant Ceramide Preparation Using Mild Acid Hydrolysis of Glucosylceramides and Characterization with LC-MS/MS. Planta Medica.

Tesfaye Gabriel, Anteneh Belete, Gerd Hause, Reinhard H.H. Neubert, Tsige Gebre-Mariam: Isolation and Characterization of Cellulose Nanocrystals from Different Agro-Industrial Byproducts. Carbohydrate Polymers.

Raphael Shedafa, Eliangiringa Kaale, Mary Justin Temu, Peter Imming, Joseph Sempombe: Discrimination of Tanzanian Black Tea According to Geographical Origin by Near-Infrared Spectroscopy and HPTLC Methods. Advance Journal of Food Science and Technology.

Raphael Shedafa, Eliangiringa Kaale, Mary Justin Temu, Peter Imming, Joseph Sempombe: Seasonal Variations of Caffeine and L-Theanine Contents in Tanzanian Black Teas. Hindawi Journal of Spectroscopy.

Abrham Temesgen, Anteneh Belete, Tsige Gebre-Mariam: Physicochemical and Drug Loading Characteristics of Local Starches Hydrophobically Modified with Different Alkyl Chains.

Mamo Feyissa, Teferi Gedif, Tsige Gebre-Mariam, Kaleab Asres: The traditional medicine practitioners’ knowledge and use of medicinal plants for management of HIV/AIDS and related illness in Metekel Zone, Northwest Ethiopia: Exploratory Study. BMC Complementary and Alternative Medicine.

Mamo Feyissa, Teferi Gedif, Tsige Gebremariam, Kaleab Asres: The Use of herbal medicine and determinant factors among HIV/AIDS and TB patients while on conventional treatment in Metekel Zone, Northwest Ethiopia: Cross-sectional Study. Hindawi Evidence-Based Complementary and Alternative Medicine.

Boingotlo Raphane, Pelonyane Ralenyena, Chris Richter, Bjӧrn Juncke, Ian Tietjen, Kerstin Andrae-Marobela: Anacardic acids from the African traditional medicinal plant Ozoroa insignis Delile mediate potent in vitro antiviral activity against HIV-1c and HIV-1b targeting host cell factors. Journal of Ethnopharmacology.

Barbara Ngwenya, Boingotlo Raphane, Kerstin Andrae-Marobela: Concurrent use of antiretroviral drugs and traditional medicine: A traditional healer’s perspective.


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