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PROJECT OBJECTIVES

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The aim of the TRI‐SUSTAIN project is to develop a novel three‐pronged integrated approach towards the goals of bioeconomic value‐chains, ecological and therapeutic sustainability, accompanied by a Graduate School.

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LATEST NEWS

November 2022: New Publication in Plants

Mthandazo Dube and Boingotlo Raphane, both PhD students from TRISUSTAIN published an article in Plants journal.

Schistosomiasis and soil-transmitted helminths are some of the priority neglected tropical diseases targeted for elimination by the World Health Organization. Although Botswana has a modern healthcare system, many people rely on traditional medicine to treat worm infections and schistosomiasis. In this study, ten plant species used by traditional health practitioners against worm infections were collected and tested against a set of species in vitro. Extracts of two plants, Laphangium luteoalbum and Commiphora pyaracanthoides, displayed promising anthelmintic activity against newly transformed schistosomas and adult Schistosoma mansoni. L. luteoalbum displayed 85.4% activity at 1 μg/mL against Newly Transformed Schistosoma, while Commiphora pyracanthoides displayed 78.5% activity against adult S. mansoni at 10 μg/mL. The anthelmintic activity shown by the plant samples demonstrates the importance of traditional medicine, as traditional health practitioners have knowledge about which plants to use against various ailments. Further investigations need to be carried out in order to identify the active principles in the plant extracts and validate the safety of the plant extracts through toxicological studies.
https://www.mdpi.com/2223-7747/11/21/2945   

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November 2022: Successful PhD Defense

Alphonce Marealle from TRISUSTAIN has successfully defended his doctoral thesis. In his work, he describes the Search for Potential Anti-HIV-1 and Antimycobacterial Compounds from Selected Tanzanian Medicinal Plants. The study was supervised by Profs. Mainen Moshi, Ester Innocent (both MUHAS) and Kerstin-Andrae-Marobela (UoB). A kind compliment goes to Dr. Alphonce Marealle for his achievements. We appreciate his contribution to the project and wish him the very best for his future career.

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• Project news - Archive

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PROJECT PARTNERS

• Martin Luther University Halle-Wittenberg (MLU)

• Addis Ababa University

• Muhimbili University of Health and Allied Sciences (MUHAS)

• University of Botswana

• Leibniz Institute of Plant Biochemistry (IPB)

• Institute for Applied Dermatopharmacy (IADP)

• Univations GmbH

• Salvation Enterprises (PTY) LTD

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PUBLICATIONS

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LINKS

• Report on the 3rd Tri-Sustain Gradual School on the website of German Embassy in Botswana - German version    

• Report on the 3rd Tri-Sustain workshop on the website of German embassy in Botswana - English version    

• Article in Campus Halensis about the Guest Professorship of Prof. Esther Innocent at the Martin-Luther-University in Halle    

• Article in Pharmazeutische Zeitung about the second Tri-Sustain Gradual School in Ethiopia

• Article in Campus Halensis about the first Gradual School in Tanzania    

• Press release to the project start

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FUNDED BY

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